The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Parkinson's Disease Progression Model
Study Rationale:
The rich and longitudinal (gathered over time) dataset available through the Parkinson's Progression Markers Initiative provides a unique opportunity to gain insights into the... -
Target Advancement Program, 2018Role of 5-alpha Reductase 1 in the Therapy of Neurodegeneration and Levodopa-induced Dyskinesias
Study Rationale:
The two main types of the enzyme 5α-reductase (5αR) play a key role in the production of steroids in the brain and other organs. In pre-clinical testing, we found that inhibitors of... -
Research Grant, 2018Using Deep Learning to Evaluate Changes Associated with Parkinson’s Disease
Study Rationale:
Recent advances in artificial intelligence and, in particular, in one of its methods called deep learning offer exciting opportunities for the diagnosis and treatment of Parkinson’s... -
Research Grant, 2018Developing TLR2-Blocking Drugs to Reduce Alpha-synuclein-Induced Inflammation in Parkinson's Disease
Promising Outcomes of Original Grant: 100 words)
Synucleinopathies, including Parkinson's disease (PD), is a group of disorders affecting the central nervous system (CNS). These disorders share one key... -
Research Grant, 2018Examining GCase Activity in People with REM Sleep Behavior Disorder
Study Rationale:
Approximately 80 percent of people with REM sleep behavior disorder (RBD) will develop a neurological disorder such as Parkinson's disease (PD). GBA mutations are the most frequent... -
Research Grant, 2018Studying GBA Pseudogene as a Controller of GBA and Alpha-synuclein
Study Rationale:
Mutations (changes) in the GBA gene are the most common genetic risk factor for Parkinson’s disease (PD). GBA has a clone called pseudogene, a similar stretch of DNA that, unlike the...
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Our funding programs support basic, translational and clinical research from academia and industry.