The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2017Studying Alpha-synuclein Oligomers Using Oligomer-binding Antibodies
Study Rationale:
Alpha-synuclein, the sticky protein that clumps in the cells of people with Parkinson's disease (PD), has long been implicated in the development of PD. Alpha-synuclein clumps vary in... -
LRRK2 Biology Consortium, 2017Developing a LRRK2-deactivating Vitamin for the Treatment of Parkinson’s Disease
Study Rationale:
One of the most common inherited causes of Parkinson’s disease (PD) is defect in the LRRK2 protein caused by changes, or mutations, of the LRRK2 gene. These LRRK2 mutations cause the... -
Research Grant, 2017Using Antibodies to Confirm Sticky Alpha-synuclein as the Cause of Parkinson's Disease
Study Rationale:
It is well known that the alpha-synuclein protein clumps in the cells of people with Parkinson's disease (PD), but it is unclear what prompts it to clump. Researchers believe that in... -
Computational Science, 2017Using Mathematical Tools to Explain the Variability in Parkinson’s Disease Symptoms and Progression
Study Rationale:
Parkinson’s disease (PD) symptoms and progression vary greatly, making each Parkinson’s experience unique. The goal of this study is to winnow out the most relevant factors... -
LRRK2 Biology Consortium, 2017Describing the Structure and Function of LRRK2
Study Rationale:
Although leucine-rich repeat kinase 2 (LRRK2) is the greatest known genetic contributor to Parkinson's disease (PD), little is known about its structure and function. To better... -
Research Grant, 2017Using Neural Cells to Test New Drugs that Activate PINK1 and Parkin
Promising Outcomes of Original Grant:
Even though most people with Parkinson's disease (PD) do not have a genetic mutation -- a change in their DNA -- that causes the disease, genes can influence the...
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Our funding programs support basic, translational and clinical research from academia and industry.