The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2016Identification of Tear Biomarkers for Individuals with Parkinson's Disease
Study Rationale:
Prior to the appearance of classic movement abnormalities like tremor and slowness, those with Parkinson's suffer from non-motor symptoms, such as altered function of the... -
Research Grant, 2016Study of Alpha-synuclein in the Dorsal Neostriatum
Promising Outcomes of Original Grant:
In February 2013, Luk et al. published in Science that administration of synthetic alpha-synuclein into pre-formed fibrils in pre-clinical models was sufficient to... -
Therapeutic Pipeline Program, 2016Effect of HDAC Inhibition in Models of Parkinson's Disease
Study Rationale:
Numerous publications have linked the family of epigenetic enzymes known as HDACs (histone deactylases) to the underlying pathology of Parkinson's. This study will test the efficacy of... -
Therapeutic Pipeline Program, 2016Cognitive Behavioral Therapy for Anxiety Disorders in Parkinson's Disease
Study Rationale:
Anxiety disorders occur in up to 35 percent of people with Parkinson's disease and can have a negative impact on gait, involuntary movements, motor fluctuations and quality of life... -
Therapeutic Pipeline Program, 2016Rehabilitation Treatment for Airway Protection in Parkinson's Disease
Study Rationale:
Aspiration pneumonia is a leading cause of death in persons with Parkinson's disease (PD). One of the main reasons people with PD develop aspiration pneumonia is that they often have... -
Research Grant, 2016GBA Meta-analysis Initiative: Charting a Path to Success for Clinical Trials in Patients with GBA-PD
Promising Outcomes of Original Grant:
We ascertained the associations between GBA mutations and cognitive and motor outcomes in seven large cohorts representing 2,304 patients with PD (including 221...
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Our funding programs support basic, translational and clinical research from academia and industry.