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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Evaluating a Microbial Biomarker in Blood Samples for Parkinson’s Disease

    Study Rationale: Diagnosing Parkinson’s disease (PD) currently involves evaluation by movement disorder specialists and assessment based on physical examination and questionnaires. This approach is...

  • Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Using Data from the LEAPS Project to Improve the Accuracy of Assays that Measure Alpha-synuclein

    Study Rationale: The scientific and clinical research community working on Parkinson’s disease (PD) is in need of biomarkers to facilitate the monitoring of disease progression and efficacy of...

  • Research Grant, 2022
    Developing a Strategy to Determine Why Melanoma and Parkinson's Disease Occur Together

    Study Rationale: Having melanoma increases the risk for Parkinson's disease (PD)—and vice versa. The cellular basis for this association is not known. To identify the key cellular events that enhance...

  • Expanding Biological Understanding of Parkinson's Disease, 2022
    Characterization of the Contributions of Alpha-synuclein and Tau Aggregation in a Preclinical Model of Parkinson’s Disease Progression

    Study Rationale: Motor difficulties are not the only symptoms experienced by people with Parkinson’s disease (PD); up to 80% eventually develop dementia. This progression to dementia is associated...

  • Target Advancement Program, 2022
    Mining for Protein Aberrations in Parkinson’s Disease Using Large-Scale Protein Databases

    Study Rationale: Deficient clearance of misfolded alpha-synuclein aggregates contributes to the pathology of Parkinson’s disease (PD). But broader disturbances in proteostasis—the balanced production...

  • Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Resolution of Parkinson-associated Loci and Creation of Predictive Models Using Multi-omic Data Analyses

    Study Rationale: Genetic studies have allowed us to understand better the genetic risk of suffering from Parkinson’s disease. However, for most of the findings we do not know the biological meaning or...

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