The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2010LRRK2 Biochemical Studies (Invitrogen/Nichols Collaboration)
Objective/Rationale:
Mutations in the gene for LRRK2 are one of the most common genetic causes of PD. However, little is known about the biological function of LRRK2 in cells or how LRRK2 biological... -
MJFF Research Grant, 2010Generation and Characterization of iPS Neurons from PINK1- and Parkin-linked Parkinson's Disease
Objective/Rationale:
Recent reports have demonstrated that skin cells from patients with Parkinson’s disease can be reprogrammed into pluripotent stem cells (iPS) and subsequently differentiated into... -
MJFF Research Grant, 2010Generation and Characterization of iPS Neurons from PINK1- and Parkin-linked Parkinson's Disease
Objective/Rationale:
Recent reports have demonstrated that skin cells from patients with Parkinson’s disease can be reprogrammed into pluripotent stem cells (iPS) and subsequently differentiated into... -
MJFF Research Grant, 2010Probing the Function of SGK1 and its Relationship to LRRK2 and Parkinson’s Disease
Objective/Rationale:
Genetic testing of 3,500 Parkinson’s disease (PD) patients revealed that mutations in serum glucocorticoid-regulated kinase 1 (SGK1) gene reverts the risk of getting Parkinson’s... -
MJFF Research Grant, 2010Support for your Collaboration on Proof-of-concept clinical trial on the use of the 5-HT1A/1B Partial Agonist Eltoprazine for Treatment of L-DOPA-induced Dyskinesias. - Linked to Bjorklund CIA 2009
Objective/Rationale:
We have identified a new potential drug target for Parkinson's disease -- receptors located on the so-called serotonin neurons in the brain -- for alleviation of involuntary... -
MJFF Research Grant, 2010Generation of Phosphospecific LRRK2 Antibodies
Objective/Rationale:
LRRK2 (Leucine-Rich Repeat Kinase 2) is a protein thought to be involved in regulating signaling pathways in cells. Mutations in the gene for LRRK2 are associated with some...
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Our funding programs support basic, translational and clinical research from academia and industry.