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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • RRIA (Rapid Response Innovation Awards), 2013
    Role of GSK-3beta in Parkinson’s Disease

    The protein GSK-3beta has not previously been linked to Parkinson’s disease (PD). Recently, we have studied pre-clinical models with high levels of GSK-3beta throughout the brain. At a younger age [up...

  • MJFF Research Grant, 2013
    Validation and Characterization of Exosomal Alpha-synuclein as a Diagnostic Marker for Parkinson’s Disease

    Parkinson’s disease (PD) is characterized by aggregation of the intracellular alpha-synuclein protein and subsequent neurodegeneration. Recent findings suggest that extracellular alpha-synuclein forms...

  • Rapid Response Innovation Awards, 2012
    Polyglutamine Repeats and Parkinson Disease

    Objective/Rationale:             
    Trinucleotide repeat expansion is a gene mutation where the codons (the groups of DNA components that correspond to amino acids) exceed the maximum of a certain gene...

  • Dyskinesia LEAPS, 2012
    Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease

    Objective/Rationale: 
    Dyskinesia is a term used to describe involuntary movements that develop as side effects of dopamine drugs used to treat Parkinson's disease. Dyskinesias are frequent and...

  • Research Grant, 2013
    Ubiquitous, Inexpensive Non-invasive Technologies for Objective Detection and Monitoring of Parkinson’s Symptoms

    Objective/Rationale:
    For doctors to diagnose and treat Parkinson’s, they need reliable tests. Unfortunately, testing the symptoms of Parkinson’s at a specialist’s office/clinic is expensive and time...

  • Research Grant, 2013
    Prion-like Dissemination of Synuclein Pathology: A Non-human Study

    Objective/Rationale:
    Parkinson’s disease (PD) is characterized by the loss of midbrain dopaminergic neurons and the presence of aggregates named Lewy bodies. This pathology is believed to drive the...

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