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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Parkinson's Global Genetics Discovery, 2019
    Genome-wide Association Study in Parkinson’s Disease Among an East Asian Population

    Study Rationale:
    The majority of the genome-wide association studies in Parkinson’s disease have included European ancestry cases and controls only, and targeted studies in East Asian populations only...

  • Therapeutic Pipeline Program, 2019
    Clinical Development of AKST4290 as a Novel Parkinson’s Therapeutic

    Study Rationale:
    There is clear evidence that the immune system plays an important role in the development and progression of Parkinson's disease. Novel therapies targeting the recruitment of immune...

  • Research Grant, 2019
    Restoring the Nigrostriatal Pathway with Living Micto-tissue Engineered Axonal Tracts Supplement

    Promising Outcomes of Original Grant:
    The classic motor deficits of Parkinson’s disease (PD) are caused by degeneration of dopamine neurons, resulting in the loss of part of the neurons called axonal...

  • Research Grant, 2019
    Longitudinal Examination of Problems that Bother People with Parkinson’s

    Study Rationale:
    Using the Fox Insight research platform, we extracted and analyzed reports in patients’ own words about what problems bother them and how these problems affect their daily functioning...

  • Research Grant, 2019
    Validation of Microglial CRAC Channels as a Therapeutic Target for Parkinson’s Disease

    Study Rationale:
    Inflammation of the central nervous system mediated by microglial cells is a major feature of Parkinson’s disease. Vivreon Biosciences is developing Parkinson’s disease therapeutics...

  • Research Grant, 2016
    Investigation of the Role of PINK1-dependent Phosphorylation of Rab GTPases in Parkinson’s Disease

    Study Rationale:
    Mutations in the PINK1 gene lead to Parkinson’s disease. PINK1 belongs to a special class of enzymes known as protein kinases. We recently found that PINK1 targets a family of enzymes...

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Our funding programs support basic, translational and clinical research from academia and industry.

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