The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Specification, Patterning, and Maintenance of Midbrain Dopam, 2004Analysis of the Progressive Postnatal Loss of Nigral Dopaminergic Neurons in Engrailed Mutant Mice
The hallmark of Parkinson's disease is the slow progressive loss of dopaminergic neurons in the substantia nigra. The cellular mechanism and the molecular triggers leading to the demise of the cells...
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LEAPS, 2004Encapsulated GDNF-Producing Cells for Neuroprotection in Parkinson's Disease
This LEAPS team (representing seven academic institutions, a research foundation, and a private company) is seeking to develop a novel therapy for Parkinson's disease based on the implantation of...
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Edmond J. Safra Global Genetics Consortia, 2004Collaborative Studies of a Chromosome 5 PD Susceptibility Gene
During the past decade it has become clear that genetic factors are important in determining whether an individual will develop Parkinson's disease. Several research groups are now trying to identify...
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Edmond J. Safra Global Genetics Consortia, 2004Global Genetics Consortium: Collaborative pooled analysis on the association of the alpha-synucleingene REP1 variant and Parkinson’s disease
Our Edmond J. Safra Global Genetics Consortium aims to determine: 1) whether variability in the promoter region of the alpha-synuclein gene confers susceptibility for Parkinson's disease; 2) whether...
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Edmond J. Safra Global Genetics Consortia, 2004Gene-Environment Interaction in PD: Predicting the Onset, Prognosis and Response to Treatment
Parkinson's disease is a complex and heterogeneous disorder. Discovery of genes that result in rare inherited forms of PD has led to new insights into the cause of disease and the promise of effective...
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Edmond J. Safra Global Genetics Consortia, 2004Gene Expression in Parkinson's Disease
"Gene chip" technology allows for expression analysis of thousands of genes on a single glass slide, known as microarray. Together with our collaborators we have already assayed 4.2 million data...
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Our funding programs support basic, translational and clinical research from academia and industry.