The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2022Pharmacokinetics, Food Effects, Safety and Tolerability of Aggregation Inhibitor Anle138b in Parkinson´s Disease
Study Rationale:
Pathological alpha-synuclein aggregates, called Lewy bodies, are a hallmark of Parkinson’s disease (PD) and a promising target for therapeutics. Anle138b is a compound that inhibits... -
Fall 2021 RFP: Expanding Biological Understanding of PD, 2022Exploring How Mutations in Genes Associated with Parkinson’s Disease Alter the Activity of Other Genes
Study Rationale: Population studies have identified genetic changes that raise an individual’s risk of developing Parkinson’s disease (PD). However, this information doesn't help people if we don’t...
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Diversity, Equity and Inclusivity in Parkinson's research, 2022Multiculturalism, Reported Cognitive Complaints and Predictors of Cognitive Decline Following Deep Brain Stimulation
Study Rationale: Cognitive decline is common in people with Parkinson’s disease (PD), and changes in thinking and performance on objective cognitive tests reported by individuals and their family are...
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Diversity, Equity and Inclusivity in Parkinson's research, 2022Racial Disparities in Parkinson’s Disease Care Among Asian Americans and Native Hawaiian/Pacific Islanders: A Retrospective Analysis of Hospitalization Data and Pilot Project for Prospective Cohort Study
Study Rationale: The state of Hawai’i is ethnically diverse, with a mix of Southeast Asian, East Asian and North Americans, in addition to distinct indigenous Native Hawaiians and Pacific Islanders...
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Therapeutic Pipeline Program, 2022Developing Selective Ion Channel Blockers that Reduce Neuroinflammation in Parkinson’s Disease
Study Rationale: We are developing novel therapeutics to reduce brain inflammation and enhance the survival and function of brain cells in Parkinson’s disease (PD). Studies over the past decade have...
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Spring 2022 RFP: Expanding Biological Understanding of Parkinson's Disease, 2022Assessing Genetic Predisposition to Gastrointestinal Symptoms in Young-onset and Late-onset Parkinson’s Disease
Study Rationale: Constipation is a common, nonmotor manifestation of Parkinson’s disease (PD) that can impact the quality of life of people with the condition. Yet little is known about the genetic...
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Our funding programs support basic, translational and clinical research from academia and industry.