The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2017Protein Homeostasis and the Ubiquitination Pathway in Parkinson's Disease
Study Rationale:
Parkinson's disease (PD) involves accumulation of toxic proteins in cells in specific areas of the brain. These cells normally have protective mechanisms to remove these toxic... -
Target Advancement Program, 2016Assessing the PINK1 Pathway in Parkinson
Study Rationale:
Rare mutations in the PINK1 gene cause familial (inherited) Parkinson's disease (PD). However, it is not known if PINK1 contributes to the development of idiopathic (no known cause) PD... -
Research Grant, 2016Investigation of LRRK2 as a Regulator of Dendritic Cell Function
Promising Outcomes of Original Grant:
Myeloid cells (white blood cells) of the immune system include monocytes, neutrophils and dendritic cells found in circulation, as well as microglia (immune system... -
Research Grant, 2018Genetic Factors that Influence Inherited Parkinson's Disease Associated with Changes in the GBA gene
Study Rationale:
Changes (variants) in the GBA gene are among the most common genetic factors that affect the risk of developing Parkinson's disease (PD). Individuals who carry the same GBA variants... -
Research Grant, 2018The Role of Lysosomal Proteins in Inherited Parkinson's Disease Associated with Changes in the GBA gene
Study Rationale:
Changes (mutations) in the GBA gene are among the most common and important genetic factors leading to Parkinson's disease (PD). The GBA gene directs the production of the... -
iPD Program, 2018Impact of Genetic Changes Linked to Both Crohn's Disease and Parkinson's Disease on the LRRK2 Protein
Study Rationale:
Recent research suggests an about 30 percent higher rate of Parkinson's disease (PD) in people with Crohn's disease (CD) than in those without CD. This could be, at least in part...
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Our funding programs support basic, translational and clinical research from academia and industry.