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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2022
    Identifying Novel Target Genes and Compounds for Controlling the Motor Symptoms of Parkinson’s Disease

    Study Rationale: Understanding neurological conditions has been among the most difficult challenges in modern medicine. The brain contains more than 86 billion nerve cells that form the neural...

  • Summer 2022 RFP: The Edmond J. Safra Movement Disorders Research Career Development Award, 2022
    Tracking Eye Movements and Pupil Responses as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders

    Study Rationale: We do not currently have accurate tests to diagnose Parkinson’s disease (PD) and the conditions which mimic it (atypical parkinsonism) at a very early stage. Similarly, we do not have...

  • Research Resources, 2022
    Neural Network Imaging Analysis in Parkinson’s Disease Associated with Parkin Mutation

    Study Rationale: Clinical imaging biomarkers are desperately needed to provide a non-invasive means of assessing therapeutic efficacy in clinical trials for Parkinson’s disease (PD). Recent studies...

  • Fall 2020 RFA: Therapeutic Pipeline Program-Pre-Clinical, 2022
    Assessing a Novel Strategy for Noninvasive Stimulation of Dopamine-producing Neurons in Preclinical Models of Parkinson’s Disease

    Rationale: Parkinson’s disease (PD) is caused by the progressive degeneration of the dopamine-producing neurons responsible for initiating and refining voluntary movements. Treatments based on drugs...

  • Summer 2022 RFP: The Edmond J. Safra Movement Disorders Research Career Development Award, 2022
    Assessing Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes

    Study Rationale: Inherited Parkinson-dystonia syndromes are rare but ideal models for studying genetically complex disorders, such as Parkinson’s disease (PD), as their underlying cause — mutation in...

  • Research Grant, 2022
    (Supplement) Self-reported Perceptions and Self-reported Outcomes on Motor and Non-motor Symptoms in the Parkinson's Disease Continuum: A Systematic Review of Mixed Methods

    Study Rationale: People are unique in the way they experience quality of life. Throughout the progression of Parkinson's Disease, patients and their care partners have different perceptions of motor...

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