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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Understanding LRRK2 Biology, 2009
    Identification of LRRK2 Substrates in Pre-clinical Models of Parkinson's Disease

    Objective/Rationale
    Mutations in the LRRK2 gene are a common cause of familial and sporadic Parkinson’s disease. The LRRK2 protein can function as a kinase in vitro and certain familial mutations may...

  • Understanding LRRK2 Biology, 2009
    Functional Analysis of LRRK2

    Objective/Rationale
    LRRK2 is a gene that, when not working properly, causes Parkinson’s disease. However, the function of this large gene and its involvement in the disease process is virtually...

  • Understanding LRRK2 Biology, 2009
    Development of Biochemical Assays for LRRK1

    Objective/Rationale
    Studies over the last several years have identified the protein kinase LRRK2 as a potential target for Parkinson’s disease therapeutics.  While targeting kinases has been a...

  • Biomarkers, 2009
    T-Cell Receptors Changes as a Biomarker of Parkinson's Disease

    Objective/Rationale:
    The diagnosis of PD is based on clinical characteristics because there are no reliable blood tests for early diagnosis or to follow the progressive course of the disease. Along...

  • Rapid Response Innovation Awards, 2009
    Defining Genetic Factors for PD in a Conserved Population

    Objective/Rationale
    The identification of genes underlying risk for Parkinson’s disease (PD) helps to further the understanding of this complex disorder, with the discovery of new genes contributing...

  • Program-non-specific Funding, 2009
    Data Repository for Experimental Data

    Objective/Rationale
    Synthesizing biomedical data into effective discoveries is greatly hampered by the way science is both reported in research articles and stored in databases. Articles do not...

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