The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Development of Progressive Pre-clinical Models of PD, 2006Generation of Transgenic Mice with Selective and Progressive Loss of Nigrostriatal Dopaminergic Neurons
Mutations in the alpha-synuclein gene are responsible for rare, dominantly inherited forms of familial Parkinson's disease, designated PARK1 and PARK4. Furthermore, alpha-synuclein is also the major...
-
Development of Progressive Pre-clinical Models of PD, 2006P1 Artificial Chromosome Transgenic Mice as models for Progressive Parkinson Disease
Although most cases of Parkinson's disease occur without a family history, there are examples of highly hereditary forms of the disease. One rare form of hereditary PD is caused by alterations in a...
-
Development of Progressive Pre-clinical Models of PD, 2006LRRK2 and PD Genetic Pre-clinical Models
The cause of Parkinson's in most patients is unknown, but in a small percentage of cases (three to five percent), mutation in a specific gene is causal. Several genes have been conclusively linked to...
-
Fast Track, 2001Lentiviral Delivery of Neublastin to MPTP-Treated Pre-clinical models
Parkinson's disease (PD) results primarily from striatal dopamine (DA) insufficiency and degeneration of dopaminergic neurons within the substantia nigra pars compacta. The cause of PD still remains...
-
Fast Track, 2001Rapid Parkinson's Drug Screen Using Parkin Knockout Stem Cells
Autosomal recessive loss-of-function mutations in the parkin gene are the most common cause of familial Parkinson's disease (PD), which is characterized by selective loss of dopaminergic (DA) neurons...
-
Fast Track, 2001PET Neuroimaging Study of the Brain Serotonin Transporter in Parkinson's Disease: Relationship to Clinical Depression
Approximately 40% of patients with Parkinson's disease (PD) suffer from depression, which in many cases is more disabling than the impairment of motor function. Since the original discovery by Oleh...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.