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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2008
    A Randomized, Double-Blind, Trial of Nexalin® vs. Placebo in Subjects with Early Parkinson's Disease

    Objective/Rationale:
    While the oral medications to treat PD are often quite effective in treating the physical symptoms (motor symptoms) such as tremor and stiffness, they may be associated with side...

  • Rapid Response Innovation Awards, 2008
    Effects of noradrenergic or serotoninergic system lesions combined with NS lesions on rodent models of 'non-motor'-like symptoms

    Objective/Rationale:
    Parkinson’s disease is widely attributed to neuropathy of dopaminergic neurones in the nigrostriatal (NS) pathway. Degeneration of noradrenergic and serotonergic neurones in the...

  • Rapid Response Innovation Awards, 2012
    A Genetic Strategy to Restore Impaired Noradrenergic Function by Increasing Expression of Noradrenergic Phenotypes in the Locus Coeruleus in Parkinson’s Disease Pre-clinical Models

    Objective/Rationale:
    Compelling evidence demonstrated that a dysfunction of the locus coeruleus (LC)-
    noradrenaline (NE) system in the brain not only contributes to alterations in
    cognitive and motor...

  • Fast Track, 2002
    Testosterone Therapy in Parkinson's disease

    The University of Florida Movement Disorders Center will be following up the promising results of two preliminary studies of testosterone replacement therapy in male Parkinson's disease patients in a...

  • Research Grant, 2018
    The Effect of Psychological Stress on the Symptoms of Parkinson's Disease

    Study Rationale:
    Many people with Parkinson's disease (PD) experience chronic stress and associated disorders, such as depression, anxiety or both. Furthermore, many people with PD notice worsening of...

  • LEAPS, 2011
    Supplement to 'Discovery of mGluR4 Potentiators for Symptoms & Side Effects and Disease-Modifying Treatment of PD'

    Promising Outcomes of Original Grant:
    Activation or potentiation of metabotropic glutamate receptor 4 (mGluR4) is a promising new strategy for both Symptoms & Side Effects and disease-modifying...

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