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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2017
    Blood Proteins for the Treatment of Parkinson’s Disease

    Study Rationale & Design:
    Components of blood have been found to improve health and enhance multiple biological functions in pre-clinical studies of age-related decline. Blood plasma has been...

  • Improved Biomarkers and Clinical Outcome Measures, 2019
    Mitochondrial Complex 1 PET Imaging in Parkinson’s Disease

    Study Rationale:
    Methods are needed for imaging early pathological changes in the brain. With such brain imaging, we would be able to determine whether medications are protecting against progression...

  • Parkinson’s Disease Therapeutics Pipeline Program, 2024
    Therapeutic Development of Novel STING Inhibitors to Treat Parkinson's Disease Neuroinflammation

    Study Rationale: Brain inflammation plays an important role in the pathology and progression of Parkinson’s disease (PD). One of the key proteins involved in this inflammatory process is STING...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    BIOLOGY IS THE DISEASE: Identifying Biological Endophenotypes Based on Alpha-synuclein and AD Pathology Profiles and Evaluate NSD-ISS Stage 3-6

    Study Rationale: In the era where we aim to define diseases by biology and modifying treatment options become available for neurodegenerative diseases, the clinicopathological heterogeneity in alpha...

  • Therapeutic Pipeline Program, 2016
    Effect of HDAC Inhibition in Models of Parkinson's Disease

    Study Rationale:
    Numerous publications have linked the family of epigenetic enzymes known as HDACs (histone deactylases) to the underlying pathology of Parkinson's. This study will test the efficacy of...

  • Parkinson’s Disease Therapeutics Pipeline Program, 2025
    ACT-02 as a Disease-modifying Therapy for Parkinson’s

    Study Rationale: Parkinson’s disease (PD) is a complex neurodegenerative disorder marked by the loss of dopaminergic neurons, however the underlying exact reasons are still not fully understood...

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