The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2016Identification of Tear Biomarkers for Individuals with Parkinson's Disease
Study Rationale:
Prior to the appearance of classic movement abnormalities like tremor and slowness, those with Parkinson's suffer from non-motor symptoms, such as altered function of the... -
Improved Biomarkers and Clinical Outcome Measures, 2017Developing Biosignatures of Parkinson's Disease Using Sense of Smell
Study Rationale:
Recent reports of "super-smelling powers" published in The Lancet Neurology has triggered the idea of a specific "musky" scent in the sebum, an oily skin secretion, of those with... -
LRRK2 Biology Consortium, 2017Kinase Activity-mediated Changes in LRRK2-Parkinson's and Sporadic Parkinson's Cells and Rab Protein Function
Promising Outcomes of Original Grant:
Our previous studies have demonstrated deficits in cohesion, positioning, and polarity (important characteristics of cells that help regulate function) in... -
Target Advancement Program, 2018Hexosaminidase as a Therapeutic Target for Parkinson's Disease
Study Rationale:
Hexosaminidase (HEX) is a protein that is stored inside lysosomes, tiny bubbles inside the cell responsible for getting rid of its waste. A lack of HEX is associated with Sandhoff... -
Research Grant, 2018Registry for the Advancement of Deep Brain Stimulation Therapy in Parkinson's Disease
Study Rationale:
Deep brain stimulation (DBS) is a surgical therapy that delivers small electrical pulses to the brain to decrease movement symptoms of Parkinson's disease (PD). Registry for the... -
Improved Biomarkers and Clinical Outcome Measures, 2018Developing a Test for Circular RNA, a Possible Biomarker of Parkinson's Disease
Study Rationale:
Circular RNA (circRNA) is a recently discovered type of RNA, a molecule that plays an important role in protein production. CircRNAs are abundant in the brain and builds up when...
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Our funding programs support basic, translational and clinical research from academia and industry.