The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Charting a Path to Success for Clinical Trials in Patients with Inherited, GBA-linked Parkinson's Disease: PPMI Supplement
Promising Outcomes of Original Grant:
The original study is ongoing.Objectives for Supplemental Investigation:
We aim to determine whether fatty molecules called sphingolipids can serve as biomarkers --... -
Alpha-Synuclein Biology and Therapies, 2018Sugars Cause Alpha-Synuclein to Form Less-Toxic Clumps
Study Rationale:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Chemicals that stick to alpha-synuclein make it toxic to brain cells. Sugar-like... -
Research Grant, 2018Improving Existing LRRK2 Tests with Novel Reagents
Promising Outcomes of Original Grant:
The goal of our original study was to determine the best conditions for collecting and processing blood cells intended for testing the function of LRRK2, a protein... -
Research Grant, 2018Studying Lipids in the Blood as Indicators of Pre-clinical and Early Parkinson’s Disease
Study Rationale:
There is a need for biomarkers -- disease measures -- that indicate and can help diagnose early-stage Parkinson’s disease (PD). Identification of PD during this stage, in the absence... -
Research Grant, 2018Creating a Fluorescent Tag for Protein GCase in Blood Cells
Study Rationale:
About 10 percent of people with Parkinson disease (PD) carry changes in the GBA gene that cause malfunction of a protein called glucocerebrosidase (GCase). People with Parkinson’s... -
Research Grant, 2018A Role of Protein Parkin in Innate Immunity
Study Rationale:
There is growing evidence that some genes associated with Parkinson's disease (PD) also play a role in immunity. Changes in PRKN -- a gene that directs the production of protein...
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Our funding programs support basic, translational and clinical research from academia and industry.