The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018The Interplay between Genetic and Environmental Mechanisms in Parkinson’s Disease
Study Rationale:
Genes implicated in Parkinson's disease (PD), such as alpha-synuclein, DJ-1 and LRRK2, strongly influence the effect of environmental toxins, such as pesticide rotenone know to cause... -
Research Grant, 2018Discovery of Microbiome Biomarkers for Parkinson's Disease
Study Rationale:
The gut microbiome -- a community of microorganisms living in the gastrointestinal tract -- influences the development of the nervous system, affects behavior and contributes to... -
Target Advancement Program, 2018Hexosaminidase as a Therapeutic Target for Parkinson's Disease
Study Rationale:
Hexosaminidase (HEX) is a protein that is stored inside lysosomes, tiny bubbles inside the cell responsible for getting rid of its waste. A lack of HEX is associated with Sandhoff... -
Research Grant, 2018Registry for the Advancement of Deep Brain Stimulation Therapy in Parkinson's Disease
Study Rationale:
Deep brain stimulation (DBS) is a surgical therapy that delivers small electrical pulses to the brain to decrease movement symptoms of Parkinson's disease (PD). Registry for the... -
Improved Biomarkers and Clinical Outcome Measures, 2018Developing a Test for Circular RNA, a Possible Biomarker of Parkinson's Disease
Study Rationale:
Circular RNA (circRNA) is a recently discovered type of RNA, a molecule that plays an important role in protein production. CircRNAs are abundant in the brain and builds up when... -
Target Advancement Program, 2018Evaluating the Role and Therapeutic Potential of Natural Killer Cells in Parkinson's Disease
Study Rationale:
Natural killer (NK) cells are immune cells that defend the body against external and internal threats. While the number of NK cells is increased in Parkinson's disease (PD), it...
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Our funding programs support basic, translational and clinical research from academia and industry.