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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2017
    Studying Alpha-synuclein Oligomers Using Oligomer-binding Antibodies

    Study Rationale:
    Alpha-synuclein, the sticky protein that clumps in the cells of people with Parkinson's disease (PD), has long been implicated in the development of PD. Alpha-synuclein clumps vary in...

  • LRRK2 Biology Consortium, 2017
    Developing a LRRK2-deactivating Vitamin for the Treatment of Parkinson’s Disease

    Study Rationale:
    One of the most common inherited causes of Parkinson’s disease (PD) is defect in the LRRK2 protein caused by changes, or mutations, of the LRRK2 gene. These LRRK2 mutations cause the...

  • Access to Data and Biospecimens, 2015
    BioFIND: Analysis of A-beta, Tau and P-tau in CSF Samples

    Study Rationale: Mixed pathology is common in all neurodegenerative diseases including Parkinson’s disease (PD).  Three cerebrospinal fluid (CSF) biomarkers, Ab1-42, t-tau and p-tau181, provide an...

  • Access to Data and Biospecimens, 2016
    MicroRNAs as biomarkers of the prodromal stage of Parkinson disease’

    Study Rationale:

    MicroRNAs (miRNAs) are small regulatory RNAs controlling gene expression. We have recently reported reduced  miRNAs levels in serum from Parkinson disease (PD) patients, and also from...

  • Research Grant, 2017
    Using Antibodies to Confirm Sticky Alpha-synuclein as the Cause of Parkinson's Disease

    Study Rationale:
    It is well known that the alpha-synuclein protein clumps in the cells of people with Parkinson's disease (PD), but it is unclear what prompts it to clump. Researchers believe that in...

  • Computational Science, 2017
    Using Mathematical Tools to Explain the Variability in Parkinson’s Disease Symptoms and Progression

    Study Rationale: 
    Parkinson’s disease (PD) symptoms and progression vary greatly, making each Parkinson’s experience unique. The goal of this study is to winnow out the most relevant factors...

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