The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Developing New Tracers for Imaging Synapses in the Brain
Study Rationale:
A synapse is a point of contact between a nerve cell and another cell that allows them to communicate. In the brain, changes in the number of synapses (synaptic density) are associated... -
Research Grant, 2018Searching for New Causes of LRRK2-associated Parkinson's Disease
Study Rationale:
Mutations (changes) in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD) and cause dysfunction in the LRRK2 protein. However, not all LRRK2 mutations cause the... -
Alpha-synculein Biology and Therapies, 2018Supporting Alpha-synuclein Attachment to Synaptic Vesicles for the Treatment of Parkinson's Disease
Study Rationale:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Researchers believe that alpha-synuclein clumps can damage nerve cells in the... -
Research Grant, 2018Autophagy and Mitochondrial Dysfunction as Potential Therapeutic Targets in Inherited Parkinson's Disease
Study Rationale:
Mutations (changes) in the gene that controls the production of enzyme glucocerebrosidase (GCase) are the most common risk factor for inherited Parkinson's disease (PD). We have... -
Research Grant, 2018Assessing Proteins LRRK2, GCase and Cytokines in Immune Cells
Study Rationale:
Leucine-rich repeat kinase 2 (LRRK2) and glucocerebrosidase (GCase) are two proteins linked to an increased risk of developing Parkinson’s disease (PD). Both proteins are produced by... -
Target Advancement Program, 2017Toll-like Receptor Inhibition to Block Alpha-synuclein-induced Pro-inflammatory Signaling and Cytokine Release
Study Rationale:
Synucleinopathies, including Parkinson's disease (PD), are a family of central nervous system (CNS) degenerative disorders characterized by alpha-synuclein protein-containing...
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Our funding programs support basic, translational and clinical research from academia and industry.