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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Access to Data and Biospecimens, 2015
    Immunogenetic Determinants of Disease Risk in Parkinson’s Disease

    Study Rationale: 

    There is growing indication that the immune system plays a role in the development and progression of Parkinson’s disease with recent genome-wide association studies identifying...

  • Improved Biomarkers and Clinical Outcome Measures, 2015
    Defining a PD-specific Breath Fingerprint of Underlying Inflammatory and Neurodegenerative Processes

    Study Rationale:                   

    Breath analysis has the potential to be a powerful non-invasive screening tool to help a clinician determine the need for additional more invasive tests, a tool...

  • Therapeutic Pipeline Program, 2015
    RQ-00000010 for Gastroparesis and Constipation in Parkinson’s Disease

    Study Rationale:                   
    Constipation and gastroparesis (slow stomach emptying) are common non-motor symptoms of Parkinson’s disease (PD). These symptoms cause troublesome gastrointestinal...

  • Access to Data & Biospecimens, 2015
    Whole Genome Sequencing and Analysis of the PPMI Prodromal and Genetic Cohorts, PPMI Genetic Registry and the LRRK2 Cohort Consortium

    Study Rationale:                   

    This work aims to provide genetic information for the whole genome and assess the role of the identified genetic information in Parkinson disease. To do this...

  • Access to Data & Biospecimens, 2015
    Evaluation of Alpha-synuclein and Hemoglobin Levels in CSF, Plasma and Saliva samples from the BioFind Cohort

    Study Rationale:                   

    Alpha-synuclein pathology plays a major role in Parkinson’s disease (PD). Recent studies suggest that measurement of alpha-synuclein in biological fluids (e.g...

  • Research Grant, 2014
    Development of an MgluR4 PET Radioligand

    Study Rationale:                   
    mGluR4 is a glutamate receptor that is believed to be a potential therapeutic target for Parkinson’s disease (PD). Developing an imaging tracer may allow researchers...

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