The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2021Hidden Sorrows of Covid-19: Impact of Stress on Parkinson’s Disease Progression
Study Rationale: People living with Parkinson’s disease (PD) are very sensitive to stress, which worsens motor symptoms (such as tremor) and leads to anxiety and depression. Studies in animals suggest...
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Research Grant, 2020Targeting of the Raphe-Cortical Pathway to Reduce Levodopa-Induced Psychosis
Study Rationale:
Parkinson’s disease is best known as a movement disorder, yet non-motor symptoms such as anxiety, depression and psychosis afflict over 50 percent of patients and severely impact... -
Improved Biomarkers and Clinical Outcome Measures, 2019International Validation of Two Non-motor Symptom Scales in Parkinson’s Disease
Study Rationale:
Non-motor Parkinson’s symptoms can fluctuate with dopaminergic medication effectiveness. Anxiety, sadness, lack of energy and fatigue are common symptoms during the off-medication... -
Therapeutics Development Initiative, 2011Pharmacokinetics and Cognitive Side Effects of the Antidyskinetic Drug Fenobam in MPTP-treated Pre-clinical Models
Promising Outcomes of Original Grant:
The goal of our original project was to determine if a prodrug of acamprosate could inhibit levodopa-induced dyskinesias (LIDs) in a pre-clinical model. During... -
Defining Cognitive Phenotypes of Parkinson’s Disease, 2011The Relationship Between Cognitive Phenotypes of PD with Visual Hallucinations and 5HT2A Receptors in the Inferotemporal Cortex
Objective/Rationale:
The project aims to understand the mechanisms underlying cognitive deficits that are associated with visual hallucinations (VH) in Parkinson’s disease (PD). We have previously... -
Therapeutic Pipeline Program, 2015Improving Access to Depression Care in Parkinson’s Disease: A Telehealth Approach
Study Rationale:
There is a critical need for treatments that address depression and barriers to care among the approximately 5 million people living with Parkinson’s disease (PD)...
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Our funding programs support basic, translational and clinical research from academia and industry.