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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Community Fast Track, 2003
    Regulation of Dopaminergic Pathways by Eph Family Receptors

    Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson's disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also...

  • Postural Instability and Gait Disturbances, 2009
    Determining the Neural Correlates of Freezing of Gait in Parkinson's Disease Using Functional Magnetic Resonance Imaging

    Objective/Rationale:
    Freezing of Gait (FOG) in Parkinson’s disease occurs when a person’s feet become suddenly ‘frozen’ while walking or turning. FOG is a leading cause of falls, and responds poorly to...

  • Clinical Intervention Awards, 2007
    Serotonin and Sleep Disordered Breathing in Parkinson Disease

    Objective/Rationale:
    Sleep related problems are a major cause of impairment in Parkinson's disease. Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing...

  • Biomarkers Across Neurodegenerative Diseases, 2014
    Cortical and Functional Distinctions in Alzheimer’s and Parkinson’s Diseases

    Study Rationale:
    Alzheimer’s disease (AD) and Parkinson’s disease (PD) are clinically distinct disorders, but their pathologies overlap considerably. Understanding how these overlaps relate to the two...

  • Alpha-synuclein Pathology, 2014
    Contrasting Pathological Versus Normal Alpha-synuclein Assemblies

    Study Rationale:                   
    Parkinson’s disease (PD) is characterized by Lewy bodies composed of the protein alpha-synuclein in dopamine-producing nerve cells. The protein aggregates are also...

  • Computational Science, 2017
    Analyzing Data from the Parkinson’s Progression Markers Initiative to Identify Subtypes of Parkinson’s Disease

    Study Rationale:
    Parkinson's disease (PD) presents and progresses variably, so no two people with Parkinson's have the same disease. The diversity of PD clinical manifestations makes the disease more...

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