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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2013
    Alpha-synuclein Picobody: A Novel Blood-Brain Barrier Permeable Diagnostic Ligand for Parkinson's Disease

    Objective/Rationale:             
    The presence of the blood-brain barrier (BBB) has been an insurmountable impediment to successful drug delivery to the central nervous system. To circumvent the BBB...

  • Dyskinesia Challenge, 2013
    Imaging Dyskinesia in People with Parkinson's Disease

    Objective/Rationale:             
    Levodopa-induced dyskinesias are abnormal involuntary movements that may develop with levodopa therapy for Parkinson's disease (PD). Recent studies on pre-clinical...

  • LRRK2 Pharmacodynamic Assays, 2013
    LRRK2-associated Mitochondrial DNA Damage as a Phenotype for Unbiased Screening

    Objective/Rationale:  
    The normal functions of LRRK2 are poorly understood, and the mechanism(s) by which LRRK2 mutations cause PD are unclear. Also, therapeutic development has been hampered by the...

  • Biosample and Tissue Resource, 2013
    Is Dysphagia in Parkinson’s Disease Caused by Lewy Pathology in the Upper Aerodigestive Tract?

    Objective/Rationale:             
    We have recently demonstrated that the nerves supplying the throat are directly affected in Parkinson’s disease (PD) by the same microscopic process that affects the...

  • Research Grant, 2013
    Virtual Research Visits

    Objective/Rationale:             
    The Michael J. Fox Foundation’s Fox Trial Finder is designed to facilitate and increase the participation of individuals with Parkinson’s disease in clinical trials...

  • Research Grant, 2013
    Long-term Cortical Recording in Parkinson’s Disease Patients Using a Totally Implanted Device

    Objective/Rationale:             
    Deep brain stimulation (DBS) of basal ganglia structures is an effective treatment for Parkinson’s disease (PD). However, its mechanism of action is still unclear...

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Our funding programs support basic, translational and clinical research from academia and industry.

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