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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2013
    DNA Methylation Profiling from Blood as a Source for Biomarker Discovery in Parkinson’s Disease

    Objective/Rationale:            
    Epigenetic mechanisms regulate when the information stored in the DNA is expressed to ensure the proper function of the cells, including neurons in the brain. Recent...

  • Research Grant, 2013
    Advancement of Quantitative Disease Progression Modeling of Parkinson’s Disease

    Objective/Rationale:             
    In clinical trials, the progression of Parkinson’s disease (PD) is primarily measured by the change in total Unified Parkinson Disease Rating Scale (UPDRS) score...

  • Research Grant, 2013
    Dynamics of Alpha-synuclein Aggregation in Dopamine Neuron Degeneration and Recovery

    Promising Outcomes of Original Grant:
    Alpha-synuclein is the central player for Parkinson’s disease. Therapies to decrease levels of alpha-synuclein are promising in curing PD. However, it is unknown...

  • Rapid Response Innovation Awards, 2013
    DNA Methylation as a Biomarker for Parkinson’s Disease

    Objective/Rationale:             
    We will test the hypothesis that whole blood DNA methylation in Parkinson’s disease (PD) will be altered at specific sites compared to either healthy controls or to...

  • Rapid Response Innovation Awards, 2013
    Feeding with Clostridium Leptum for Restoring the Integrity of the Striatal Dopaminergic System in a Pre-clinical Model of Parkinson’s Disease

    Objective/Rationale:             
    Inflammation contributes to the pathogenic process of Parkinson’s disease (PD). Increased numbers of anti-inflammatory regulatory T cells (Tregs) has been associated...

  • Synuclein Therapeutic Acceleration Program, 2013
    Quinpramine for Parkinson’s Disease

    Objective/Rationale:             
    A part of Parkinson’s disease progression involves abnormal aggregation of normal brain proteins into knots of insoluble irritant material. The protein involved in...

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Our funding programs support basic, translational and clinical research from academia and industry.

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