The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Accelerating Biological Understanding and Therapeutic Translation For Parkinson’s Disease- Biology, 2025(SUPPLEMENT) Validation of LRRK2 Modifiers as Potential PD Therapeutic Targets
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Research Grant, 2025Applying the Neuronal Alpha-synuclein Disease Integrated Staging System in Multiple System Atrophy
Study Rationale: The neuropathological hallmark feature of Parkinson’s disease (PD) is the accumulation of a misfolded protein called alpha-synuclein in neurons, which qualifies PD as a neuronal...
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Research Grant, 2025(SUPPLEMENT) Enhancing Brain Clearance Mechanisms to Limit Parkinson Disease Progression
Study Rationale: Recent evidence has shown that people with Parkinson’s disease have a buildup of toxic proteins in their brains, as a result of impaired waste clearance mechanisms. Linked to this...
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Research Grant, 2025Clinical Evaluation of 18F-FD4 as a Potential Alpha-synuclein PET Imaging Biomarker
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iPSC Phenotyping Environmental Exposure Program, 2025Assessing PD-relevant Toxicants on Neurons and Microglia and their Crosstalk
Study Rationale: We know that genetics plays a role in risk of Parkinson’s disease (PD) but does not explain every case, leading to the suggestion that genes work within the context of other exposures...
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Specification, Patterning, and Maintenance of Midbrain Dopam, 2004Studies on Endogenous Neurogenesis in the Adult Mammalian Substantia Nigra
We have published evidence for a slow, endogenous generation of new dopaminergic nerve cells in the adult mouse midbrain, i.e. the nerve cell type lost in Parkinson's disease. (PNAS 100, 7925-7930...
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Our funding programs support basic, translational and clinical research from academia and industry.