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We are charting the path to a future free from Parkinson’s. Your support will get us there.

Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Clinical Intervention Awards, 2007
    Serotonin and Sleep Disordered Breathing in Parkinson Disease

    Objective/Rationale:
    Sleep related problems are a major cause of impairment in Parkinson’s disease. Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing…

  • Postural Instability and Gait Disturbances, 2009
    Determining the Neural Correlates of Freezing of Gait in Parkinson's Disease Using Functional Magnetic Resonance Imaging

    Objective/Rationale:
    Freezing of Gait (FOG) in Parkinson’s disease occurs when a person’s feet become suddenly ‘frozen’ while walking or turning. FOG is a leading cause of falls, and responds poorly to…

  • Computational Science, 2017
    Analyzing Data from the Parkinson’s Progression Markers Initiative to Identify Subtypes of Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease (PD) presents and progresses variably, so no two people with Parkinson’s have the same disease. The diversity of PD clinical manifestations makes the disease more…

  • Access to Data & Biospecimens, 2017
    Klotho and Parkinson’s disease

    Study Rationale:                   

    Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying age-related declines in cellular and tissue functioning…

  • Community Fast Track, 2004
    The role of nociceptin/orphanin FQ in regulation of motor behavior and induction of parkinsonism

    Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide discovered in the mid 90’s, which activates a G-protein coupled receptor, the NOP receptor. N/OFQ and its receptor are diffusely expressed…

  • LRRK2 Cohort Consortium Resource Request, 2013
    Alpha-synuclein and Other Biomarkers in Biological Samples of LRRK2 Parkinson’s Disease

    Objective/Rationale:
    Cerebrospinal fluid (CSF) biomarkers of Alzheimer’s pathology have been investigated in Parkinson’s disease (PD), and abnormal CSF protein levels (tau and phosphorylated tau, beta…

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