The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Antibody Comparison, 2011Analysis of LRRK2 Antibodies
Objective/Rationale:
There is great hope that drugs targeting an enzyme termed LRRK2 may be useful in treating Parkinson’s disease (PD). There is therefore intense research taking place to better... -
Antibody Comparison, 2011LRRK2 Immunocytochemistry in Cultured Neurons
Objective/Rationale:
Several antibodies have been identified that recognize Leucine-Rich Repeat Kinase 2 (LRRK2), but uncertainty persists as to whether such antibodies are reliable in detecting ... -
Antibody Comparison, 2011Characterization of LRRK2 Monoclonal Antibodies in Pre-clinical Brain Tissue
Objective/Rationale:
Mutations in Leucine Rich Repeat Kinase 2 (LRRK2) are implicated in Parkinson’s disease in humans. At present we understand neither the normal nor the pathogenic role of LRRK2. We... -
Rapid Response Innovation Awards, 2011Salivary Gland Biopsies as a Diagnostic Test for Parkinson's Disease
Objective/Rationale:
We have previously found that in autopsied patients with Parkinson’s disease the hallmark finding in the brain (Lewy body or Lewy neurite) is also found in the submandibular gland... -
Rapid Response Innovation Awards, 2011Inflammatory Insults in Early Life and Susceptibility to Parkinson's Disease in Later Life
Objective/Rationale:
Researchers have reported that early-life inflammation in the brain may increase a risk for development of Parkinson’s disease (PD), but the mechanisms involved remain unclear. ... -
Research Grant, 2014Phase IB Follow-up Study to Assess Boost Immunization with AFFITOPE® PD01A
Study Rationale:
PD01A is an alpha-synuclein-targeting vaccine. Accumulation and/or aggregation of alpha-synuclein is central to the pathogenesis of Parkinson’s disease, and its reduction is expected...
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Our funding programs support basic, translational and clinical research from academia and industry.