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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2011
    Novel Neuroprotective Cell-Penetrating Peptides

    Objective/Rationale:
    Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) is currently one of the most potent factors protecting and rescuing neurons in pre-clinical models of Parkinson’s...

  • Research Grant, 2011
    Comparing Cognitive Scales in the MUSTARDD-PD Study

    Objective/Rationale:
    Some people with Parkinson’s may develop dementia during their disease course. Being able to detect problems with mental function at an early stage, to monitor and to reliably...

  • Rapid Response Innovation Awards, 2011
    Testing Novel Compounds for Noninvasive Delivery of Small Interfering RNA into CNS

    Objective/Rationale:

    Small interfering RNA (siRNA) molecules have been successfully used to target specific genes in cell culture. However, the lack of specificity for siRNA to cells and lack of...

  • MJFF Research Grant, 2011
    Phenotypic Characterization of BAC LRRK2 Transgenic Pre-clinical Models

    Objective/Rationale:

    Mutations in the protein leucine-rich repeat kinase 2 (LRRK2) are the most common cause of inherited Parkinson’s disease (PD). Interestingly, the penetrance LRRK2 mutations and...

  • Rapid Response Innovation Awards, 2011
    Defining PARKIN Substrates Through Systematic Quantitative Proteomics

    Objective/Rationale:
    The PARK2 (Parkin) gene is frequently mutated in Parkinson’s disease. Several lines of evidence indicate that Parkin functions to catalyze the conjugation of the small protein...

  • Rapid Response Innovation Awards, 2011
    Intestinal Microbiota, Permeability and Alpha-synclein Aggregation in Parkinson's Disease

    Objective/Rationale:
    Changes in the intestinal system may occur early in the development of Parkinson’s disease. The intestinal system is important to (1) maintain normal “healthy” bacteria; and (2)...

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Our funding programs support basic, translational and clinical research from academia and industry.

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