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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2023
    Characterizing the Immune Cells Present in the Blood and Cerebrospinal Fluid of People with Parkinson's Disease Associated with Mutations in LRRK2

    Study Rationale: Several studies have demonstrated that people with Parkinson’s disease (PD) have an altered frequency of immune cells in the blood. In addition, immune cells that normally patrol the...

  • Translational Pipeline Program, 2023
    Identifying Small Molecule Inducers of Autophagy and Lysosomes

    Study Rationale: Neurons keep themselves healthy and free of damaged cellular materials using an internal garbage collection system called autophagy and internal recycling centers called lysosomes...

  • Research Grant, 2023
    Measuring Quality of Life in People with Parkinson’s Disease: State of the Art and Areas for Development

    Study Rationale: Scales to measure quality of life are important tools for research. However, it is unclear whether currently available scales for measuring quality of life take into account the...

  • Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023
    Validation of KLK6 as a New Therapeutic Target for Parkinson’s Disease

    Study Rationale: Alpha-synuclein is the main protein that aggregates and forms Lewy bodies, the hallmark histological characteristics of Parkinson disease (PD). Multiple experimental studies suggest...

  • Novel PET Tracer Development Program, 2023
    Monitoring Glucocerebrosidase Engagement in Parkinson’s Disease

    Study Rationale: Glucocerebrosidase is an enzyme that is essential for maintaining healthy lipid metabolism throughout the human body. In Parkinson’s disease (PD), the efficiency of this protein is...

  • Research Grant, 2023
    Enhancing Access to Meaningful Data: Nebraska Parkinson’s Disease Registry

    Study Rationale: Nebraska’s Parkinson’s Disease Registry (NPDR) will roll out a new electronic data collection system, enforce state statutes requiring that physicians participate in reporting...

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Our funding programs support basic, translational and clinical research from academia and industry.

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