The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2020Assessment of Brain Tau Burden in Parkinson's Disease with or without a LRRK2 Mutation using [18F]MK-6240 PET Imaging
Study Rationale:
The precise mechanisms of cellular damage in Parkinson's disease remain unclear. Research has shown that abnormal forms of the protein alpha-synuclein accumulates in brain cells in... -
Research Grant, 2020Targeting TNFR2 in a Model of Parkinson’s Disease
Study Rationale:
In previous research, we demonstrated that the protein tumor necrosis factor receptor 2 (TNFR2) plays an essential role in reducing inflammation in the peripheral and central nervous... -
Therapeutic Pipeline Program, 2020Development of Novel Parkin Activators
Study Rationale:
In Parkinson’s disease, brain cells die when their mitochondria (structures that create energy for the cells) are damaged and cannot be removed efficiently. An enzyme called parkin... -
Target Advancement Program, 2020The Role of Cannabinoid Receptor 2 in Inflammatory Responses Triggered by Alpha-synuclein
Study Rationale:
There is growing interest in the anti-inflammatory properties of cannabis-related compounds as a potential therapy for Parkinson’s disease (PD). Cannabis, or marijuana, acts on... -
Therapeutic Pipeline Program, 2020Therapeutic Swallow Sensor
Study Rationale:
Trouble swallowing is a common problem for people with Parkinson’s disease, occurring in up to 80 percent of cases. Swallowing problems can lead to drooling, increased risk of... -
Target Advancement Program, 2020Evaluating the Role of Natural Killer Cells in Parkinson's Pathology
Promising Outcomes of Original Grant:
Our original study investigated whether immune cells called human natural killer (NK) cells play a protective role on the nervous system in Parkinson’s disease...
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Our funding programs support basic, translational and clinical research from academia and industry.