The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Therapeutics Development Initiative, 2007Effects of PYM50028 in Reversing Dopaminergic Neuronal Degeneration and Behavioral Impairments in Parkinson's Disease
Objective/Rationale:
The objective of this project is to assess the effects of oral administration of Cogane™ (PYM50028) in reversing the changes in the brain involved in Parkinson’s disease (PD) and... -
Therapeutics Development Initiative, 2007Development of Inhibitors of Alpha-Synuclein Toxicity to Treat Parkinson's Disease
Objective/Rationale:
Many of the symptoms of Parkinson’s disease are caused by the death of dopamine (DA) producing neurons that control movement. Alpha-synuclein is a protein which accumulates in the... -
Therapeutics Development Initiative, 2007NF-kB as target for Parkinson's Disease Therapy
Objective/Rationale:
Chronic inflammation mediated by microglial cells is the fundamental process contributing to the death of dopamine producing neurons in the brain. Production of inflammatory... -
Community Fast Track, 2006The Role of Serotonin Neurons in the Induction of Dyskinesia in Grafted and L-DOPA-primed Animals
Levodopa, which is the most commonly used medication for patients with Parkinson's disease, is a beneficial therapy, but as the disease progresses it can be the cause of debilitating involuntary...
-
MJFF Research Grant, 2006A Phase II Clinical Trial of Neurturin (NTN) Gene Therapy for PD
Objective/Rationale:
Neurotrophic factors including neurturin (NTN) have been shown to effectively augment the function and prevent the death of dopaminergic nigrostriatal neurons in animal models of... -
MJFF Research Grant, 2006The Unified Dyskinesia Rating Scale (UDysRS): Clinimetric Testing Program
In Parkinson’s disease, one of the most troubling clinical issues for prevention and management is drug-induced dyskinesia. Dyskinesias are abnormal and involuntary movements that relate in part to...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.