The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarkers, 2005Longitudinal Assessment of Olfactory Dysfunction in Early PD
The impaired ability to smell (also known as olfaction) is increasingly recognized as a consistent feature of the symptomatology of Parkinson's disease (PD). Moreover, the appearance of olfactory...
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Biomarkers, 2005Development of Lewy Bodies MRI Imaging Agents for the Early Diagnosis of PD & Related Disorders
Parkinson's disease and related conditions are the most common movement disorders. Pathological studies reveal abundant protein deposits in the affected neurones, mainly formed by the protein alpha...
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Biomarkers, 2005Reduction of NURR1 mRNA in Human Peripheral Blood Lymphocytes as a Biomarker of PD
Parkinson's disease is a common neurodegenerative disease in adults, affecting over 1 million people in the United States. The neuropathology in the brain has been progressing long before the clinical...
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The Role of Inflammation in Parkinson's Disease, 2005Development of a Dominant-Negative TNF Lentiviral Approach
Because TNF inhibitors are not believed to cross the blood-brain barrier, an orally administered TNF-based therapy is not currently possible. The Foundation has awarded supplemental funding to drive...
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Molecular Mechanisms of Dyskinesia in Parkinson's Disease, 2004In Vitro Electrophysiological Studies in Experimental Models of Dyskinesias
Although levodopa is one of the most effective therapies for Parkinson’s disease, particularly in the early stages, chronic treatment leads to the development of dyskinesias or movement abnormalities...
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Specification, Patterning, and Maintenance of Midbrain Dopam, 2004Identification of Novel Determinants for Dopamine Neuron Generation in Vivo and in Embryonic Stem Cells
Understanding how the different cells of the brain are generated during embryonic development is one of the fundamental questions in biology. Recent studies have elucidated several key mechanisms...
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Our funding programs support basic, translational and clinical research from academia and industry.