The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2003Morphology Specific Antibodies as Potential Therapeutics
Parkinson's Disease has been correlated with the over expression and misfolding of the protein a-synuclein. This protein is abundantly produced in nerve cells in the brain and is the major component...
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Community Fast Track, 2003Anti-inflammatory Effects of Nicotine in Parkinson’s Disease
Parkinson's disease (PD) is a progressive, debilitating movement disorder resulting from the death of the dopamine-synthesizing neurons and, consequently, dopamine deficiency in the basal ganglia, i.e...
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Community Fast Track, 2003Development of the Midbrain Dopaminergic Pathways
Parkinson's disease is a result of degeneration of the midbrain dopaminergic (DA) neurons. In the treatment of Parkinson's disease, replacing lost neurons is a promising therapy. However, the progress...
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Community Fast Track, 2003In vivo investigation of DJ-1 function in DJ-1 knockout mice
Two genetic mutations in the DJ-1 gene have been identified earlier this year that can cause early-onset Parkinson's disease. Since both mutations are believed to cause loss of function of the DJ-1...
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The Role of Inflammation in Parkinson's Disease, 2003The Role of TNF-Mediated Dopaminergic Neurotoxicity in Parkinson's Disease: Novel Anti-TNF Biologics as Biochemical Tools and New Therapeutic Agents
Loss of dopamine-producing neurons is a hallmark of Parkinson's disease and inflammation-driven oxidative stress is believed to play a significant role in this neurodegenerative process.
Strong...
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Community Fast Track, 2003Osteopontin as a regulator of the inflammatory response to nigral celldegeneration
The cause of nerve cell death in the substantia nigra in Parkinson's disease remains unknown. However, one feature of the degenerative process is the onset of inflammation in this brain region due to...
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Our funding programs support basic, translational and clinical research from academia and industry.