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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2026
    Deep Mutational Scanning of TMEM175

    Study Rationale:                   

    Parkinson’s disease develops through a combination of ageing, environmental factors, and genetic risk. One gene linked to Parkinson’s is TMEM175, which encodes an...

  • Research Grant, 2026
    Cell Type Meta-eQTL Study in Human Brains

    Study Rationale:                                                

    Parkinson’s (PD) genome-wide association study (GWAS) with ~1.5 million subjects identified 90 PD risk signals with ~7,000 non-coding PD...

  • Research Grant, 2026
    Genetically Encoded Fluorescent Biosensors for Live-cell, Subcellular Detection of Distinct α-synuclein Aggregation States

    Study Rationale:                   

    Alpha-synuclein (aSYN) is a critical protein in health and Parkinson’s disease (PD). aSYN has a soluble form and a series of increasingly aggregated forms. These...

  • Research Grant, 2026
    Validation of ADx LRRK2 and pS1292 LRRK2 SiMOA Assays Using Standardized Sample Set

    Study Rationale:                   

    The goal of this project is to use standardized and validated samples to determine if the LRRK2 and pS1292 LRRK2 assays available through ADx Neurosciences can...

  • Spring 2025 RFA: Molecular MRI Biomarker Program, 2026
    Exploring Dynamic Brain Metabolism in PD

    Study Rationale:                   

    Existing non-invasive imaging methods can only measure steady-state metabolic concentrations. There is a need to more precisely dynamic measure brain metabolite...

  • Research Grant, 2026
    Discovery of Selective PET Imaging Agents for Alpha-Synuclein
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