The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2014Inhibition of Striatal-Enriched Phosphatase (STEP) to Improve Parkinson-Related Cognitive Dysfunction
Study Rationale:
As the enzyme striatal-enriched phosphatase (STEP) may be abnormally elevated in aged parkinsonian pre-clinical models with cognitive deficits, the possibility... -
Research Grant, 2020Parkinson’s Disease with Mild Cognitive Impairment Treated with a Nicotinic Agonist Drug
Study Rationale:
Parkinson’s disease with mild cognitive impairment (PD-MCI) is common, has important clinical consequences, and there is currently no treatment available. The underlying pathology of... -
Defining Cognitive Phenotypes of Parkinson’s Disease, 2011The Relationship Between Cognitive Phenotypes of PD with Visual Hallucinations and 5HT2A Receptors in the Inferotemporal Cortex
Objective/Rationale:
The project aims to understand the mechanisms underlying cognitive deficits that are associated with visual hallucinations (VH) in Parkinson’s disease (PD). We have previously... -
Repositioning Drugs for PD, 2011Droxidopa Treatment for Cognitive Impairment in Parkinson's Disease
Objective/Rationale:
Memory, concentration, and other cognitive operations are sometimes impaired in Parkinson's disease (PD), but available treatment options are very limited. This project will test... -
Research Grant, 2018Safety and Tolerability of GRF6021 Infusions in People with Parkinson's Disease and Cognitive Impairment
Study Rationale & Design:
Components of blood have been found to improve health and enhance multiple biological functions, including brain function, in older animals. Blood plasma has been... -
Improved Biomarkers and Clinical Outcome Measures, 2019Correlating MRI, Pathology and Cognitive Assessments toward Biomarkers of Cognitive Decline
Study Rationale:
Parkinson’s studies are working to identify magnetic resonance imaging (MRI) biomarkers for early diagnosis, disease severity and progression. However, attempts to explore how brain...
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Our funding programs support basic, translational and clinical research from academia and industry.