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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2021
    Tagging Genes Associated with Parkinson’s Disease Using the Gene-editing CRISPR Tool

    Study Rationale:
    Parkinson’s disease (PD) is caused, in part, by genetic alterations that produce defective proteins or perturb normal pathways in the brain. To determine how these alterations lead to...

  • Analysis of Patient-Reported Outcomes from Fox Insight, 2021
    Investigation of Environmental Factors in Idiopathic and LRRK2-related Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by loss of neurons in the substantia nigra, a brain region that controls motion. This loss leads to...

  • Target Advancement Program, 2021
    Pathogenic Mechanisms for Auxilin-mediated Parkinson's Disease

    Study Rationale:
    Parkinson’s disease (PD) is a prevalent neurodegenerative movement disorder. Several genetic mutations that cause PD have been identified in patients. One such mutation targets...

  • PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2021
    Characterization of PET Tracers for Alpha-synuclein and 4R Tau

    Study Rationale:
    Parkinson’s disease (PD) is a brain disease characterized by slow movement, rest tremor and stiffness. In most cases the underlying cause is an aggregation of a protein called alpha...

  • Improved Biomarkers and Clinical Outcome Measures, 2021
    Isolating Olfactory Biomarkers of Early Parkinson’s Disease

    Study Rationale:
    Recently, researchers discovered a specific set of molecules in the oily substance produced by the skin of people with Parkinson’s disease (PD). The findings stemmed from work with a...

  • PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2021
    Development of a New Class of PET Tracers for Imaging Tau and Alpha-synuclein

    Study Rationale:
    Parkinson’s disease (PD), Alzheimer’s disease and progressive supranuclear palsy are all characterized by the presence of abnormal aggregations of two proteins in the brain: alpha...

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