The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Aligning Science Across Parkinson's, 2021Gut-to-brain Circuit Contributions to Parkinson-like Phenotypes in Disease Models
Study Rationale:
Although clinicians have long reported that Parkinson’s disease (PD) does not affect the brain alone, the field has only recently started to investigate gut dysfunction in... -
Aligning Science Across Parkinson's, 2021Alpha-synuclein Effects on Gut-brain Circuits and Pre-motor Symptoms in Parkinson’s Disease
Study Rationale:
A hallmark of Parkinson’s disease (PD) is the development of abnormal deposits throughout the brain composed of the alpha-synuclein protein. This pathology can also be found in the... -
Aligning Science Across Parkinson's, 2021Olfactory Circuits: Alpha-Synuclein-Rich Neurons Respond to Environmental Triggers at the Origin of Parkinson’s Disease
Study Rationale:
To slow the progression of Parkinson's disease (PD), we need to know more about how it starts. It is well known now that many individuals with PD have had a significant reduction in... -
Aligning Science Across Parkinson's, 2021Basal Ganglia Networks in Parkinson's Disease
Study Rationale:
People with Parkinson's disease have long been known to display remarkable motor abilities under special circumstances such as smooth walking with certain visual or auditory cues... -
Aligning Science Across Parkinson's, 2021Distributed Circuit Dysfunction Underlying Motor and Sleep Deficits in a Progressive Model of Parkinson’s Disease
Study Rationale:
Parkinson’s disease (PD) begins decades before it compromises the ability to move about in the world and sleep through the night. Understanding how the dysfunction of brain circuits... -
Aligning Science Across Parkinson's, 2021Activity and Connectivity Drive Neuronal Vulnerability and Disease Progression in Parkinson’s Disease
Study Rationale:
Specific brain circuits that are highly melanized (build-up of the dark pigment neuromelanin) with age are primarily affected, particularly early, in Parkinson's disease. Models...
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Our funding programs support basic, translational and clinical research from academia and industry.