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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2019
    Biomaterial-enhanced Cellular Brain Repair for Parkinson's Disease

    Study Rationale:
    One promising approach for the treatment of Parkinson’s is to replace the cells that have died in the disease through transplantation of healthy cells into the brain. However, this...

  • Target Advancement Program, 2019
    Connexins as a New Therapeutic Target to Impede Spreading of Alpha-synuclein Pathology

    Study Rationale:
    Direct cellular connectivity has recently been implicated in the transfer of alpha-synuclein pathology associated with Parkinson’s disease. The gap junction proteins known as...

  • Research Grant, 2019
    Immune Cell Dysfunction in PINK1 Parkinson’s Models

    Promising Outcomes of Original Grant:
    In our previous project, we significantly advanced the characterization of PINK1 knockout (KO) models. We found evidence of innate and adaptive immune cell...

  • Research Grant, 2019
    Restoring the Nigrostriatal Pathway with Living Micto-tissue Engineered Axonal Tracts Supplement

    Promising Outcomes of Original Grant:
    The classic motor deficits of Parkinson’s disease (PD) are caused by degeneration of dopamine neurons, resulting in the loss of part of the neurons called axonal...

  • Research Grant, 2019
    Developing New 18F-based Brain Tracers for Imaging Synapse in the Human Brain

    Study Rationale:
    A synapse is a structure that allow nerve cells (neurons) to communicate with one another or with target cells. In the brain, changes in synaptic density are associated with a variety...

  • Parkinson's Global Genetics Discovery, 2019
    Genome-wide Association Study in Parkinson’s Disease Among an East Asian Population

    Study Rationale:
    The majority of the genome-wide association studies in Parkinson’s disease have included European ancestry cases and controls only, and targeted studies in East Asian populations only...

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Our funding programs support basic, translational and clinical research from academia and industry.

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