The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2019Deficit in Mitochondrial Transport as a Potential Measure of Parkinson's Disease
Study Rationale:
Dysfunction of mitochondria -- powerhouses of the cell -- is one of the possible causes of Parkinson's disease (PD). To supply all parts of the nerve cell with energy, mitochondria... -
Biomarkers of Protein Handling/Autophagy, Exosomes and Lipid, 2019Extracellular Vesicles Produced by Microglia as Novel Biomarkers of Parkinson's Disease
Study Rationale:
Extracellular vesicles (EVs) are small sacks that are released by all cells of the human body. They cross barriers within the body with relative ease and carry molecules that can be... -
Research Grant, 2019Transglutaminase 2 Inhibitors as a Disease-Modifying Treatment for Parkinson's Disease
Study Rationale:
Buildup and clumping of protein alpha-synuclein is a hallmark of Parkinson's disease (PD) and a likely cause of neurodegeneration and, ultimately, symptoms. It's important to know what... -
Alpha-Synuclein Biology and Therapies, 2019Alpha-synuclein-Binding Proteins on the Cell Surface as Novel Therapeutic Targets
Study Rationale:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Recent research suggests that clumps of alpha-synuclein spreads in the brain... -
Research Grant, 2019New Activators of Parkin
Study Rationale:
Parkin is a protein made by all cells in the body, including brain cells. It plays an important role in the protection of neurons through a process known as quality control. Changes... -
Research Grant, 2019Imaging Techniques to Evaluate LRRK2 Activity in Idiopathic Parkinson's Disease
Study Rationale:
Inherited mutations in the LRRK2 gene are a common cause of Parkinson's disease that presents with clinical symptoms and brain changes similar to idiopathic (cause unknown) Parkinson...
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Our funding programs support basic, translational and clinical research from academia and industry.