To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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LRRK2 KO Mouse
Mouse Model
Knockout of LRRK2 created by deletion of exons 39-40 of the LRRK2 gene in the C57BL/6N mouse strain. RRID:IMSR_JAX:016121
LRRK2 Plasmids
DNA Plasmids
DNA Plasmids encoding various LRRK2 cDNA inserts
LRRK2 T1348N Mouse
Mouse Model
Mice expressing the T1348N mutant (GTPase-dead) form of LRRK2. RRID:IMSR_JAX:021829
VPS35 D620N Mouse
Mouse Model
Mice expressing the D620N mutant form of VPS35. RRID:IMSR_JAX:023409
LRRK2 pT1491 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1491 of LRRK2.
Microtubule-Associated Protein Tau Plasmids
DNA Plasmids
DNA Plasmids encoding various MAPT cDNA inserts
VPS35 Plasmids
DNA Plasmids
DNA Plasmids encoding various VPS35 cDNA inserts
PINK1 Plasmids
DNA Plasmids
DNA Plasmids encoding various PINK1 cDNA inserts
Parkin Plasmids
DNA Plasmids
DNA Plasmids encoding various Parkin cDNA inserts
LRRK2 pT1503 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1503 of LRRK2.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic