To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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ROSA LRRK2 R1441C Mouse*
Mouse Model
Transgenic mice with human LRRK2 R1441C inserted into the endogenous Gt(ROSA)26Sor locus. Model was generated and deposited by Darren Moore at Van Andel Research Institute through the MJFF Sponsored Tools Program (available through cryorecovery).
LRRK2 Antibody (8G10)
Antibody
Mouse monoclonal antibody directed against wild-type LRRK2 using a fragment of LRRK2 (AA 100-500)
RILPL1 Antibody
Antibody
Mouse monoclonal antibody directed against total rodent/human RILPL1 protein. Suitable for immunoblot, immunoprecipitation, and immunocytochemistry experiments. This antibody is a chimeric mouse IgG2a version of the rabbit anti-RILPL1 antibody (MJF-R41-21, ab302492).
Rab 8A Antibody
Antibody
Mouse anti-Rab8A antibody that has undergone Fc species switching to develop mouse reagents from the original rabbit antibody (MJF-R22-79-3). The new chimeric antibody is approved for immunoblotting, immunoprecipitation, immunostaining, and flow cytometry and can be detected using Fc-specific secondary antibodies to mouse IgG.
AAV Mouse SNCA 3xmiR/GFP Plasmid
DNA Plasmids
Viral transgene plasmid used in the AAV Mouse SNCA 3xmiR/GFP viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit groups only. RRID:Addgene_194248
AAV Human SNCA 3xmiR/GFP Plasmid
DNA Plasmids
Viral transgene plasmid used in the AAV Human SNCA 3xmiR/GFP viral vector available through Charles River Labs (see viral vector section). This plasmid is available to non-profit groups only. RRID:Addgene_194247
EIF2AK1 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse EIF2AK1. Developed for use in immunoblotting and immunocytochemistry applications. Anticipated Availability: Q4 2027
Alpha-Synuclein O-GlcNAc T72 Antibody
Antibody
Rabbit monoclonal antibody specific to human and mouse alpha-synuclein when modified with O-GlcNAc at Threonine 72 (O-GlcNAc T72 aSyn). Developed for use in immunoblotting, immunofluorescence, and ELISA applications. This antibody development project is part of the MJFF Targets to Therapies (T2T) Initiative. Anticipated Availability: Q4 2027
AAK1 pS623 Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 623 of AAK1. This antibody failed validation and will not be made available.
ITPKB Antibody
Antibody
Rabbit monoclonal antibody directed against human ITPKB. Developed for use in immunoblotting, immunocytochemistry, and immunoprecipitation applications. This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative. Anticipated Availability: Q4 2027
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic