To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
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Alpha-Synuclein Aggregation Assay in iPSC-derived Neuron-Astrocyte Co-Culture
In Vitro Assays
High-throughput in vitro assay to detect alpha-synuclein pathology in iPSC-derived neuron and astrocyte co-culture system treated with alpha-synuclein pre-formed fibrils. Available as a fee-for-service assay. Estimated Availability: Late 2027
Alpha-Synuclein Aggregation Assay in iPSC-derived Dopamine Neurons
In Vitro Assays
High-throughput in vitro assay to detect alpha-synuclein pathology in iPSC-derived dopamine neurons treated with alpha-synuclein pre-formed fibrils. Available as a fee-for-service assay. Estimated Availability: Late 2027
Nuclear Emulsion for Autoradiography
Chemical
High-sensitivity photographic emulsion for microautoradiography studies to visualize distribution of radioactive tracers in tissue sections/cell preparations.
MHC-I H2-Kb Antibody
Antibody
Rabbit monoclonal antibody directed against mouse MHC-I H2-Kb for immunoblotting and immunostaining applications. This antibody only reacts with K-B.This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
MHC-I H2-Kb Antibody
Antibody
Rabbit monoclonal antibody directed against mouse MHC-I H2-Kb for immunoblotting and immunostaining applications. This antibody cross-reacts with K-B, K-K, K-Q, KW-28, D-D, alpha chain, D-K and H2-Q8.This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
Rab 12 pS106 Phosphospecific Antibody (WB)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine106 of the human Rab 12 protein. Suitable for immunoblot experiments.
Rab 12 pS106 Phosphospecific Antibody (WB/IP/PRM-MS/ELISA)
Antibody
Rabbit monoclonal antibody directed against human Rab12 when phosphorylated at Serine106 (pS106 Rab12). Developed for use in immunoblot, immunoprecipitation, PRM-MS, and ELISA applications.
MHC-I H2-D & H2-K Antibody
Antibody
Rabbit monoclonal antibody directed against mouse MHC-I H2-D and H2-K for immunoblotting and immunostaining applications. This antibody cross-reacts with H2-D: (D-B, D-D, H-2 class I histocompatibility antigen, alpha chain, D-P, D-K), H2-K: (K-B, K-D, K-K, K-Q, K-W28 alpha chain)], H2-L, H2-Q10, H2-Q8, H2-Q7, PH-2D-2.This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
SCD5 Antibody
Antibody
Rabbit monoclonal antibody directed against human SCD5 for immunoblotting and immunohistochemistry applications.
ATP13A2 Antibody (Ms - WB)
Antibody
Rabbit monoclonal antibody directed against mouse ATP13A2 for immunoblotting applications.This antibody development project is part of the Aligning Science Across Parkinson’s (ASAP) Initiative.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic