To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
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* = MJFF does not control pricing or terms of availability for this tool.
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Rab 10 pT73 Phosphospecific Antibody
Antibody
Mouse anti-pT73 Rab10 antibody that has undergone Fc species switching to develop mouse reagents from the original rabbit antibody (MJF-R21-22-5). The new chimeric antibody is approved for immunoblotting and immunocytochemistry and can be detected using Fc-specific secondary antibodies to mouse IgG.
Rab 10 Protein
Protein
Rab10 synthetic protein fragment (AA66-181) generated by native chemical ligation of recombinant peptides. To be used as a control with the pT73 Rab1o protein. This protein was designed and generated by X'PROCHEM.
Rab 10 ELISA*
Assay
ELISA kit designed for the quantitative measurement of Rab10 protein in human, mouse and rat cell and tissue extract samples.
pT73 Rab 10 Protein
Protein
Phospho-T73 Rab10 synthetic phosphomimetic protein fragment (AA66-181) generated by native chemical ligation of recombinant peptides. This protein was designed and generated by X'PROCHEM.
PSMF1 Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in PSMF1, including heterozygous and homozygous R242C and R231*, and homozygous knockout mutations. These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by Aligning Science Across Parkinson's (ASAP). Estimated Availability: Q1 2026.
pS65 Ubiquitin Immunoassay*
Assay
SMCxPRO® immunoassay for measurement of phospho-serine 65 Ubiquitin. Assay was developed and kindly shared by Mitokinin through the MJFF Sponsored Tools Program.
To access, complete the request form on the Millipore CADI services page.
pS65 Parkin Antibody (WB/ICC)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine65 of Parkin. Compatible with immunoblotting and immunocytochemistry applications.
PRKN Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in PRKN, including heterozygous and homozygous R275W, T240M, R42P, and P437L mutations. These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by Aligning Science Across Parkinson's (ASAP).
PPMI iPSCs
Human iPS Cell
Induced pluripotent stem cell (iPSC) lines are available through the PPMI repository. The repository includes lines from control, idiopathic PD, genetic PD (LRRK2, GBA, SNCA), genetic unaffected carriers (LRRK2, LRRK2/GBA, GBA, SNCA), and prodromal patients. Gene-revertant controls are available for select lines. An inventory of available lines can be found here: https://zenodo.org/records/10783308
PINK1 pT257 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine 257 of human PINK1. Suitable for immunoblot applications.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic