Brage S. Andresen, PhD, FRCPath, is professor of human molecular genetics and head of translational biology at SDU and CSO of Inverna Therapeutics. He holds a PhD in medicine from Aarhus University and is a fellow of the Royal Society of Pathology, UK (FRCPath).
He has more than 30 years of experience in molecular genetics with a special emphasis on regulation of normal and aberrant pre-mRNA splicing in human disease.
In recent years his lab has had a special focus on pseudo-exons and have developed software to identify them and methods to modulate the splicing of pseudo-exons as a new therapeutic approach. Prof. Andresen’s lab has developed splice switching oligonucleotides (SSOs) for general and allele-specific targeting of LRRK2 as a potential new therapy for Parkinson’s disease. Prof. Andresen has published more than 150 scientific papers and several patents.
In 2024 he co-founded Inverna Therapeutics, an RNA-medicine company, which develops RNA-precision medicines.
Associated Grants
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Development of a Sequence Specific LRRK2-targeted Parkinson's Disease Splice Switching Oligonucleotide Drugs
2025