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Dario Alessi, PhD

Director of the MRC Protein Phosphorylation and Ubiquitylation Unit at MRC Protein Phosphorylation Unit, University of Dundee

Location: Dundee United Kingdom

Dario Alessi obtained a BSc (1988) and PhD (1991) from the University of Birmingham (UK). He carried out postdoctoral studies at the University of Dundee (1991-1997), where he became fascinated by how all aspects of cell biology and human diseases are influenced by a class of enzyme called "kinases." In 1997, Dr. Alessi became a program leader at the Dundee MRC Unit and was appointed as its director in 2012. His current research focuses on understanding the roles of the LRRK2 pathway in Parkinson's disease (PD) and how knowledge of this pathway can be exploited to develop new ways to diagnose and slow the progression of this disease. Dr. Alessi is passionate about mentorship, open science, sharing and working with industry and clinicians, as well as fostering a collaborative culture. He is motivated to bring talented scientists into the PD research field and improve awareness of issues relating to equality, diversity, inclusion, gender and mental health.


Associated Grants

  • Development of G2019S Selective LRRK2 Inhibitors for the Treatment of Parkinson’s Disease

    2013


  • Combining Mass Spectrometry with Genetic and Pharmacological Approaches to Discover and Validate LRRK2 Substrates

    2012


  • Generation of Phospho-Ser65 Parkin and Phospho-Thr257 PINK1 Pre-clinical Monoclonal Antibodies and Characterization of Total PINK1 Pre-clinical Monoclonal Antibodies

    2012


  • Analysis of LRRK2 Antibodies

    2011


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