David Loeffler completed his BS in 1973 and DVM in 1975 from the University of California at Davis. He worked as a clinical veterinarian in Kinston and Mt. Airy, North Carolina from 1975-1976, then as a veterinary virologist at the Kimron Veterinary Institute in Bet Dagan, Israel from 1976 to 1978. He returned to the United States in 1978 and worked as a veterinarian in Fremont, California until 1981. He attended Cornell University from 1981-1985 and received his PhD in Immunology, followed by two years of postdoctoral training at the Cancer Center of the University of Rochester, Rochester, NY. He moved to Detroit in 1987 and worked at the Michigan Cancer Foundation from1987 to 1990. In 1990 he went to Sinai Hospital in Detroit to work in the Clinical Neuroscience Laboratory under the direction of Peter LeWitt, MD, where he remained until the hospital closed in 1999. He worked in the Department of Immunology and Microbiology at Wayne State University from 1999 to 2000, then returned to the Clinical Neuroscience Laboratory after it re-opened in William Beaumont Hospital, Royal Oak, Michigan in May 2000. His research interests include the role of complement activation and other inflammatory processes in the development and progression of neurodegenerative disorders, and the significance of Nocardia asteroides as a possible etiological agent for Parkinson's disease.