Ian G. Ganley, PhD

Ian Ganley’s laboratory studies how distinct mitophagy pathways interact mechanistically and how this interplay can be leveraged to maintain mitochondrial health. A major focus is understanding how Parkinson’s disease–associated mutations disrupt mitophagy in the brain. To support this work, his lab developed the mito-QC mitophagy reporter mouse, enabling high-resolution mapping of this critical pathway in vivo. Ian earned his PhD in biochemistry from the University of Cambridge and completed postdoctoral training at Stanford University and Memorial Sloan Kettering Cancer Center before establishing his lab at the University of Dundee, UK. His work has been recognized with the 2025 Hooke Medal and election to the Royal Society of Edinburgh.