Manolis Kellis, Ph.D., is a professor of computer science at MIT, and directs the MIT Computational Biology Group at CSAIL and the Broad Institute. His research focuses on uncovering the molecular mechanisms of human disease, enabling new therapeutics and personalized medicine through AI-driven integration of genetics, genomics, single-cell epigenomics, transcriptomics, and large-scale experiments. His work spans Alzheimer’s and Parkinson’s disease, obesity, cancer, and neuropsychiatric, cardiovascular, and immune disorders.
He has played leadership roles in major international efforts, including the Roadmap Epigenomics, ENCODE, GTEx, and Comparative Genomics projects. He has published more than 300 papers with over 200,000 citations. His honors include the US Presidential Early Career Award for Scientists and Engineers, the Mendel Medal, the NIH Director’s Transformative Research Award, and the Argo Science Award.
Kellis has received more than 20 NIH multi-year grants, and many of his trainees hold faculty positions at leading universities. For more information, visit compbio.mit.edu.
Associated Grants
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Multi-resolution Pathway-centric Biomarker Discovery for Parkinson’s Disease Diagnosis, Prognosis, Progression, and Treatment Recommendations
2026