Prabesh Kanel is a Research Assistant Professor in Radiology at the University of Michigan investigating neurological changes in healthy aging, Parkinson's disease (PD) and atypical parkinsonian syndromes. His background in mathematical/theoretical biology, computational biology, biostatistics, and bioimage analysis informs his approach to complex neuroimaging. His predoctoral work at Florida State University involved developing cerebral shape models, including a hippocampal atlas for Alzheimer's research. Postdoctoral training at the University of Michigan with Dr. Nicolaas Bohnen honed his expertise in Parkinsonism (clinical, structural/functional neuroimaging). Currently, he possesses the multimodal PET-MRI processing expertise crucial for this study. As IRB PI on several human studies, and as co-director of the UM Functional Neuroimaging, Cognitive & Mobility lab with Dr. Bohnen, he has the necessary infrastructure to succeed in research. His collaborations with movement disorder clinics at the University of Michigan and his previous collaborations with the Michigan Parkinson Foundation will ensure successful project recruitment.