Rajeshwar Awatramani, PhD, is a professor of neurology at the Northwestern University Feinberg School of Medicine. He received his PhD from the University of Pennsylvania and completed his postdoctoral training at Harvard University. The focus of his research has been the development and diversity of dopamine (DA) neurons. His lab has described the place of origin of DA neurons in the developing brain and is continuing to explore how progenitors of these cells are subdivided to give rise to the diverse adult DA neuron system. His lab also focuses on understanding DA neuron diversity. Using single cell profiling, his lab revealed the presence of putative DA neuron subtypes. To decipher the functional basis of DA neuron heterogeneity, Dr. Awatramani has developed a powerful set of intersectional genetic tools to access DA neuron subtypes and has found anatomical and functional heterogeneity even within a single anatomical cluster like the substantia nigra.
Associated Grants
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Redefining the Pathophysiological Mechanisms of Parkinson’s Disease in the Context of Heterogeneous Neuronsl Subtypes in the Substantia Nigr
2024
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Redefining Parkinson’s Disease Pathophysiology Mechanisms in the Context of Heterogeneous Substantia Nigra Neuron Subtypes
2021
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